Mifepristone is a synthetic steroid compound that acts as a competitive antagonist of progesterone receptors. Progesterone is essential for maintaining pregnancy; by blocking its action, mifepristone causes changes in the uterine lining, detachment of the embryo, and increased uterine sensitivity to prostaglandins.
Standard regimen: A single oral dose of 200 mg mifepristone, followed 24–48 hours later by misoprostol administered orally, buccally, or vaginally.
Must be used under the supervision of a qualified healthcare provider according to approved protocols.
Mifepristone 200 mg tablets are indicated for:
Medical termination of intrauterine pregnancy, typically up to 9–10 weeks gestation, in combination with Misoprostol
Management of early pregnancy failure (missed miscarriage)
Cervical ripening and labor induction (in specific medical settings, depending on local guidelines)
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